The Human Cost of Type 1 Diabetes

More than 1.25 million Americans have Type 1 diabetes. In 30 short years, we will have more than 5 million diabetic children and teenagers. An estimated 40,000 people are diagnosed with Type 1 diabetes each year. 200,000 people under the age of 20 years old have Type 1 diabetes.

These statistics are horrific.

Type 1, Juvenile diabetes was a death sentence, not too many years ago.

Type 1 diabetics are different from Type 2 diabetics. Those having Type 1 have a pancreas that is not producing insulin. Because of the increased rate of diabetes in our children the pressure is on to find new ways to treat this disease.

This article looks at Type 1 diabetes, considers different treatment options and explores the often forgotten nutritional elements.

Type 1 diabetes: Overview, symptoms, and treatment


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More Ways to Cope With Type 1 Diabetes and Low Blood Sugar …


By JANE E. BRODYOCT. 24, 2011

With all the concern these days about the nationwide epidemic of Type 2 diabetes, it’s easy to lose sight of the less common but much more serious form of diabetes called Type 1.

Long known as juvenile diabetes, Type 1 diabetes affects about one million Americans and most often begins in childhood, though the condition sometimes develops in adults. It is incurable, and it demands near-constant attention to blood sugar levels and treatment with insulin to keep them normal. A failure to do so can quickly become fatal.

Both types of diabetes involve an inability of the hormone insulin to do its job, but for different reasons. Insulin shuttles blood sugar, or glucose, from the bloodstream into the body’s cells, where it is used as fuel. In Type 2 diabetes, which can develop at any age, the pancreas usually produces an adequate supply of insulin, but body tissues become resistant to its effects, often because of excess weight or obesity. Weight loss often reverses the condition.

Rotavirus Vaccine May Protect Against Type 1 Diabetes – The New …


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An Australian study found that in children up to 4 years old, the rate of Type 1 diabetes decreased by 14 percent in the years after the rotavirus vaccine’s introduction.

By Nicholas Bakalar

The vaccine that prevents rotavirus, which can cause severe gastric problems in children, may have another benefit: lowering the risk for Type 1 diabetes in toddlers.

Read More: Rotavirus Vaccine May Protect Against Type 1 Diabetes – The New …


Making beta cells from people with type 1 diabetes | NIDDK

U.S. Department of Health and Human Services

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Scientists generated functional β (beta) cells from the skin cells of people with type 1 diabetes. In type 1 diabetes, a misguided attack by the immune system leads to the destruction of insulin-producing β cells found in clusters called islets in the pancreas. Although administration of insulin via injections or a pump is life-saving, it does not mimic the exquisite blood glucose (sugar) control of the pancreas. Therefore, scientists are pursuing strategies to replace the destroyed β cells. One way to do that is through islet transplantation—an experimental procedure using islets from a cadaveric donor. The procedure has shown promise for people with difficult-to-control diabetes, but has significant challenges: donor islet tissue is limited, and immunosuppressive medications, which have toxic side effects, are required to prevent rejection of tissue transplanted from another person. Toward overcoming the first barrier, scientists recently developed a new laboratory production method to make large quantities of β cells—called stem-cell derived β (SC-β) cells—from human stem cells. This method could, with further development, be used to make β cells from a sample of cells from a person with type 1 diabetes in the quantities needed for transplantation back into that same person. These cells would likely need protection from the autoimmune attack, but might not need toxic immunosuppressive medications to prevent rejection of the tissue.

To investigate this possibility, in new research, scientists used skin cells from three people with type 1 diabetes (T1D cells) and three people without diabetes (ND cells). By introducing specific factors into these cells and using the new large-scale production method they developed, they made the skin cells become stem cells—cells that could later become any cell type. They then, by introducing other factors, coaxed these stem cells to become SC-β cells (T1D SC-β cells and ND SC-β cells). Cells from the two different origins showed no differences in the ability to become SC-β cells, indicating for the first time that cells from a person with type 1 diabetes could be used to make SC-β cells.

Next, the scientists demonstrated that the T1D SC-β cells functioned like healthy β cells. For example, in laboratory culture, T1D SC-β cells secreted insulin in response to glucose; they also released insulin in response to diabetes drugs that are known to stimulate insulin secretion, demonstrating their potential for use in screening for new diabetes drugs. The T1D SC-β also functioned in live animals: when T1D SC-β cells were transplanted into male mice, they produced insulin in response to glucose and controlled the animals’ blood glucose levels.

Read More: Making beta cells from people with type 1 diabetes | NIDDK


A cure for type 1 diabetes a step closer

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Research into a possible cure for type 1 diabetes has taken an “important step forward,” according to the latest research by scientists at the Massachusetts Institute of Technology and Harvard University.

The study, which was published in journals Nature Medicine and Nature Biotechnology on Monday, builds on work by the Harvard Stem Cell Institute which last year discovered a way of creating beta cells (whose primary function is to store and release insulin) which could then be implanted in mice and, it is hoped in future, humans with diabetes.

Now, in the latest development, scientists and researchers at MIT and Harvard, in collaboration with other university experts, have developed an implantable device that could prevent those implanted insulin-producing cells from being attacked by the immune system for six months – effectively allowing the insulin-producing cells to do their job.

Diabetes is a lifelong condition that causes a person's blood sugar (glucose) level to become too high. Type 1 diabetes is an autoimmune disease in which the immune system kills off the insulin-producing beta cells in the pancreas. Daily injections of insulin are the primary treatment but are only partially successful in regulating patients' metabolism.

Read More: Cure for type 1 diabetes a step closer


Stem cell implant trial aims to reverse Type 1 diabetes | Vancouver …


The device created by ViaCyte contains millions of cells in packets that are implanted under the skin, in hopes they will function like pancreatic cells. The Human Trial / PNG

About 10 British Columbians with Type 1 diabetes will be surgically implanted with packets containing lab-grown cells that are coaxed into behaving like true insulin-producing pancreatic cells in hopes of reversing their disease.

The first patient to receive the implants is keen to exchange his regime of daily pinprick blood tests and insulin injections for a “handful” of pills for immune suppression.

“My blood sugar can go down all day without my noticing, so I’m always at risk for passing out among other health problems,” said Joshua Robertson. “The risks of immune suppression (medication) are well known and it’s no comparison.”

By Anahad O’Connor

New York Times News Service

Like many children, Andrew Hightower, 13, likes pizza, sandwiches, and dessert.

But Andrew has Type 1 diabetes, and six years ago, to control his blood sugar levels, his parents put him on a low-carbohydrate, high-protein diet. His mother makes him recipes with diabetic-­friendly ingredients that won’t spike his blood sugar, such as pizza with a low-carb, almond-flour crust and homemade bread with walnut flour instead of white flour.

Andrew’s diet requires careful planning — he often takes his own meals to school. But he and his parents say it makes it easier to manage his condition, and since he started the diet, his blood sugar control has markedly improved and he has had no complications requiring hospital visits.

Read More: Study: Low-carb diet beneficial to children with Type 1 Diabetes;


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Author: -rh sterling-

My name is Robert -rh- Sterling. I am divorced. I live in northeast Pennsylvania. I am a diabetic. Doctors predicted I would be dead in 10 years. I have now been a diabetic for 37 years. I defied their predictions. I am here to share my journey through the darkness of disease into the warm light of life beyond diabetes.